A comparison of intrathecal clonidine and buprenorphine as spinal anesthesia adjuvant for abdominal and lower limb surgeries

Background: Many intrathecal adjuvants are being used with local anesthetics to prolong the intraoperative anesthesia and postoperative analgesia. Clonidine buprenorphine known potentiate effects of anesthestics. Aims Objectives: This study was designed compare duration analgesia as well sensory motor block onset, hemodynamic changes, perioperative complications between clonidine when an adjuvant hyperbaric bupivacaine. Materials Methods: A randomized double-blind for 80 patients undergoing lower abdominal surgeries limb Group B receiving 50 mcg C 15 mg bupivacaine 0.5%. Student’s t-test Chi-square were comparing data. Results: The time onset post-operative significantly higher in group compared group. In present study, incidence bradycardia hypotension (P<0.05). Conclusion: Addition potentiates analgesia, block, has a longer analgesic effect clonidine.